Select Publications

 

 

 

 

 

 

Ma R, Feng D, Chen J, Zhou J, Xia K, Kong X, Hu G, Lu P. Targeting Tumor Heterogeneity by Breaking a Stem Cell and Epithelial Niche Interaction Loop. Adv Sci (Weinh). 2024 May 6:e2307452. doi: 10.1002/advs.202307452. Epub ahead of print. PMID: 38708713.

 

Li J, Ma R, Wang X, Lu Y, Chen J, Feng D, Zhou J, Xia K, Klein O, Xie H, Lu P. Sprouty genes regulate activated fibroblasts in mammary epithelial development and breast cancer. Cell Death Dis. 2024 Apr 10;15(4):256. doi: 10.1038/s41419-024-06637-2. PMID: 38600092

 

Ma R, Gong D, You H, Xu C, Lu Y, Bergers G, Werb Z, Klein OD, Petritsch CK, Lu P. LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland. Cell Rep. 2022 Feb 15;38(7):110375. PMID: 35172155.

 

Lu Y, Zhou T, Xu C, Wang R, Feng D, Li J, Wang X, Kong Y, Hu G, Kong X, Lu P. Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR. PLoS Biol. 2022 Jan 18;20(1):e3001518.PMID: 35041644

 

Lu Y, Deng R, You H, Lu P. 3D in vitro culture system to study collective migration in mammary organoid epithelium. STAR Protoc. 2021 Aug 27;2(3):100778. PMID: 34485944

 

Lu P, Lu Y. Born to Run? Diverse Modes of Epithelial Migration. Front Cell Dev Biol. 2021 Aug 12;9:704939. PMID: 34540829

 

Lu Y, Deng R, You H, Xu Y, Antos C, Sun J, Klein OD, Lu P. Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium. Cell Rep. 2020 Oct 13;33(2):108246. PMID: 33053348

 

Zhang Z, Sun W, Shi T, Lu P, Zhuang M, Liu JL. Capturing RNA-protein interaction via CRUIS. Nucleic Acids Res. 2020 May 21;48(9):e52. PMID: 32140725

 

Zhou T, Lu Y, Xu C, Wang R, Zhang L, Lu P. Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):4758-4769. PMID: 32051248

 

Shi T, Yao L, Han Y, Hao P, Lu P. Quantitative Phosphoproteomics Reveals System-Wide Phosphorylation Network Altered by Spry in Mouse Mammary Stromal Fibroblasts. Int J Mol Sci. 2019 Oct 30;20(21):5400. PMID: 31671542

 

Lu P, Zhou T, Xu C, Lu Y. Mammary stem cells, where art thou? Wiley Interdiscip Rev Dev Biol. 2019 Nov;8(6):e357. PMID: 31322329.

 

Koledova Z, Lu P. A 3D Fibroblast-Epithelium Co-culture Model for Understanding Microenvironmental Role in Branching Morphogenesis of the Mammary Gland. Methods Mol Biol. 2017;1501:217-231. PMID: 27796955.

 

Yao L, Lu P, Ling EA. Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia. PLoS One. 2016 Nov 3;11(11):e0166010. PMID: 27812200

 

Koledova Z, Zhang X, Streuli C, Clarke RB, Klein OD, Werb Z, Lu P. SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5731-40. PMID: 27621461

 

Werb Z, Lu P. The Role of Stroma in Tumor Development. Cancer J. 2015 Jul-Aug;21(4):250-3. PMID: 26222075

 

Zhang X, Martinez D, Koledova Z, Qiao G, Streuli CH, Lu P. FGF ligands of the postnatal mammary stroma regulate distinct aspects of epithelial morphogenesis. Development. 2014 Sep;141(17):3352-62. Epub 2014 Jul 30. PMID: 25078648

 

Zhang X, Qiao G, Lu P. Modulation of fibroblast growth factor signaling is essential for mammary epithelial morphogenesis. PLoS One. 2014 Apr 9;9(4):e92735. PMID: 24718286

 

Howard BA, Lu P. Stromal regulation of embryonic and postnatal mammary epithelial development and differentiation. Semin Cell Dev Biol. 2014 Jan-Feb;25-26:43-51. PMID: 24445189

 

Kim EJ, Jung HS, Lu P. Pleiotropic functions of fibroblast growth factor signaling in embryonic mammary gland development. J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):139-42. PMID: 23613170

 

Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol. 2012 Feb 20;196(4):395-406. PMID: 22351925

 

Lu P, Takai K, Weaver VM, Werb Z. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011 Dec 1;3(12):a005058. PMID: 21917992

 

Lu P, Werb Z. Patterning mechanisms of branched organs. Science. 2008 Dec 5;322(5907):1506-9. PMID: 19056977

 

Lu P, Ewald AJ, Martin GR, Werb Z. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. Dev Biol. 2008 Sep 1;321(1):77-87. PMID: 18585375

 

Lu P, Yu Y, Perdue Y, Werb Z. The apical ectodermal ridge is a timer for generating distal limb progenitors. Development. 2008 Apr;135(8):1395-405. PMID: 18359901

 

Lu P, Sternlicht MD, Werb Z. Comparative mechanisms of branching morphogenesis in diverse systems. J Mammary Gland Biol Neoplasia. 2006 Oct;11(3-4):213-28. PMID: 17120154

 

Sternlicht MD, Kouros-Mehr H, Lu P, Werb Z. Hormonal and local control of mammary branching morphogenesis. Differentiation. 2006 Sep;74(7):365-81. PMID: 16916375

 

Lu P, Minowada G, Martin GR. Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function. Development. 2006 Jan;133(1):33-42. PMID: 16308330.